SANTA CLARA, Calif. (AP) — Quarterback Brock Purdy remains limited by a toe injury and could miss his fourth straight game and sixth this season for the San Francisco 49ers as he tries to work his way back to health.

Purdy got hurt in the season opener against Seattle and missed the next two games. He returned in Week 4 and struggled in a loss to Jacksonville, coming out of that game with more pain in the toe.

Purdy missed the next three games and now is in danger of sitting out again this week when San Francisco (5-2) visits Houston (2-4) on Sunday.

“It is different dealing with a toe, but I’d say it’s steadily getting better each week,” coach Kyle Shanahan said Wednesday.

Mac Jones has started in place of Purdy and has led the Niners to four wins in five starts so far this season. Jo

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