The No. 25 Memphis Tigers (7-1, 3-1 American) and the Rice Owls (4-4, 1-3) meet Friday at Rice Stadium in Houston, Texas. Kickoff is scheduled for 7 p.m. ET (ESPN2). Let's analyze BetMGM Sportsbook's NCAA football odds around the Memphis vs. Rice odds and make our expert college football picks and predictions for the best bets.

Memphis leads the all-time series 3-2, including a 27-20 victory at the Liberty Bowl last season, pushing at most shops at a 7-point favorite as the Under (50.5) cashed. Prior to 2024, the teams hadn't met since 2012, a 14-10 Memphis home victory when the teams were each members of Conference USA. The last meeting in Houston was 2011, a 28-6 victory over the Tigers.

The Tigers topped the USF Bulls last week at the Liberty Bowl, winning 34-31 as a 3

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