A UPS MD-11 aircraft has crashed near Louisville Muhammad Ali International Airport in Kentucky, leading to a significant emergency response. Eyewitnesses have shared images on social media showing a large plume of smoke rising from the crash site. Local authorities have confirmed that injuries have been reported, prompting the Louisville Metro Police Department to urge the public to "stay away" from the area. The police have described the scene as active, with "fire and debris" present. In response to the incident, a shelter-in-place order has been issued for all residents within a five-mile radius of the airport. This order, which began shortly after 5:30 pm EST, instructs people to remain indoors due to the ongoing emergency. Reports from the scene indicate that ash is falling from the sky, as captured by a local reporter. The ash appears to be emanating from the smoke plume associated with the crash. The Louisville Metro Police Department has stated that they received over 20 calls regarding the incident. Spokesperson Matt Sanders confirmed that multiple agencies are responding to the situation. Grade Lane has been closed indefinitely between Stooges and Crittenden as emergency services continue to manage the scene. Authorities are working to assess the situation and provide updates as they become available.