(CNN) — A UPS MD-11 plane crashed shortly after take-off near the Louisville, Kentucky, airport, according to preliminary information, a source says.

UPS Flight 2976 crashed just after 5 p.m. local time and was headed to Daniel K. Inouye International Airport in Honolulu, according to a statement from the Federal Aviation Administration, which is investigating the crash along with the National Transportation Safety Board. The NTSB will lead the investigation, the FAA said Tuesday.

Louisville Metro Police Department and other agencies are responding to the reported plane crash, LMPD said in an X post . Injuries have been reported, police said.

A massive plume of black smoke is rising not far from the tarmac at Louisville Muhammad Ali International Airport, videos from CNN affiliate

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