LOUISVILLE, Ky. — A UPS cargo plane crashed and exploded in a massive fireball Tuesday while taking off from Louisville, Kentucky, killing at least seven people and injuring 11, authorities said.

UPS Flight 2976 crashed around 5:15 p.m. local time after taking off from the Louisville airport, the FAA said. The plane was headed to Honolulu. Three crew members were on board, according to UPS. Four others who were killed were not on the plane.

Among the 11 who were hurt, some had “very significant” injuries, Kentucky Gov. Andy Beshear said.

Video showed flames on the plane's left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in a huge fireball. Video also revealed portions of a building’s shredded roof next to the end of the runway

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