LOUISVILLE, Ky. — A UPS cargo plane crashed and exploded in a massive fireball Tuesday while taking off from the company’s global aviation hub in Louisville, Kentucky, killing at least four people and injuring 11, authorities said.

UPS Flight 2976 crashed around 5:15 p.m. local time after taking off from the Louisville airport, the FAA said. The plane was headed to Honolulu. Three crew members were on board, according to UPS.

A shelter-in-place order was extended to all areas north of the airport to the Ohio River. The Louisville airport is only a 10-minute drive from the city’s downtown, which sits on the river bordering the Indiana state line. There are residential areas, a water park and museums in the area.

Credit: AP A fireball erupts near airport property after reports of a pl

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