A large cargo plane with three people on board has crashed and exploded while taking off from an airport in Louisville, Kentucky, leaving at least three people dead and 11 injured.

Those numbers are expected to grow, the governor said. The plane crashed as it was departing for Honolulu from Louisville's Muhammad Ali International Airport, the US Federal Aviation Administration said.

Video showed flames on the plane's left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in a huge fireball.

Video also revealed portions of a building's shredded roof next to the end of the runway.

"We believe we have at least three fatalities. I believe that number is going to get larger," Kentucky Governor Andy Beshear said at a press briefing.

"Anyb

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