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LOUISVILLE, Ky. — A UPS cargo plane crashed and exploded in a massive fireball Tuesday while taking off from the company’s global aviation hub in Louisville, Ky., killing at least three people and injuring 11 — numbers that were likely to grow, the state’s governor said.

The plane crashed about 5:15 p.m. as it was departing for Honolulu from UPS Worldport at Louisville Muhammad Ali International Airport.

“Right now we believe we have at least three fatalities, though I believe that number is going to get larger. We have at least 11 injuries, some of them very significant," Gov. Andy Beshear said.

Video showed flames on the plane's left wing and a trail of smoke. The plane then lifted slightl

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