First responders were searching for more victims Wednesday after a UPS cargo plane crashed and exploded in a massive fireball at the company’s global aviation hub in Kentucky, killing at least nine people, authorities said.

The plane crashed about 5:15 p.m. as it was departing for Honolulu from UPS Worldport at Louisville's Muhammad Ali International Airport, the Federal Aviation Administration said.

Video showed flames on the plane's left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in a huge fireball. Video also revealed portions of a building’s shredded roof next to the end of the runway.

The death toll had risen to at least nine on Wednesday morning, and four of those killed were not on the plane, officials said. A shelter-in

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