LOUISVILLE, Ky. —

At least nine people are dead and 16 others are unaccounted for after a UPS cargo plane caught fire and crashed Tuesday while taking off from the company's distribution hub in Louisville.

The McDonnell Douglas MD-11 went down around 5:15 p.m. Tuesday as it was taking off from Louisville Muhammad Ali International Airport, heading toward Daniel K. Inouye International Airport in Honolulu, Hawaii. Advertisement

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It was fully loaded with fuel for the long flight.

Video shows flames on the plane's left wing and a trail of smoke as it lifted briefly off the ground before skidding off the runway.

The plane crashed in a massive fireball, with fire and debris quickly

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