Plumes of smoke rise from a UPS cargo plane crash at Louisville Muhammad Ali International Airport on Tuesday.

First responders searched for more victims Wednesday after a UPS cargo plane crashed and exploded in a massive fireball at the company’s global aviation hub in Kentucky, killing at least nine people and creating an inferno that consumed the enormous aircraft, authorities said.

“With the intense fire that was there, most of the things are gone,” Mark Little, chief of the Okolona Fire District in Louisville, said of the fuselage.

The plane with three people aboard crashed about 5:15 p.m. Tuesday as it was departing for Honolulu from UPS Worldport at Louisville Muhammad Ali International Airport. Video showed flames on the plane’s left wing and a trail of smoke.

The crash had a r

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