First responders are searching for more victims Wednesday after a UPS cargo plane crashed and exploded in a massive fireball at the company's global aviation hub in Kentucky, killing at least nine people and injuring 11, authorities said.

The plane crashed about 5:15 p.m. Tuesday as it was departing for Honolulu from UPS Worldport at Louisville Muhammad Ali International Airport in Louisville.

Kentucky Gov. Andy Beshear posted online Wednesday morning that 16 families who gathered at a reunification center "have reported loved ones unaccounted for."

Fire and smoke mark where a UPS cargo plane crashed near Louisville Muhammad Ali International Airport on November 04, 2025 in Louisville, Kentucky. Photo by Stephen Cohen/Getty Images

The airport is 7 miles (11.2 kilometers) from dow

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