Ex-House Speaker Nancy Pelosi Thursday announced she won’t run for reelection next year, ending a trailblazing career as one of the most powerful and effective congressional leaders in recent American history.

Pelosi, who broke the glass ceiling to become the first woman to serve as Speaker, said she was retiring after representing her beloved hometown of San Francisco in Washington, D.C. for nearly four decades.

“I will not be seeking reelection to Congress,” Pelosi, 85, said in a video address to voters.

Striking an optimistic tone, Pelosi framed her political swan song as a message of inspiration to her constituents.

She urged San Francisco to jealously guard its place as a progressive vanguard as Democrats fight back against President Trump’s right-wing second-term agenda.

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