New accounts show pre-tax profits at Regeneron Ireland DAC last year increased by 56pc to $4.09bn.

Revenues rose by 8pc, from $11.15bn to $12.15bn.

The accounts show the firm is a substantial contributor of the Exchequer and its corporation tax charge for 2024 totalled $608.18m.

The Pillar Two international corporation tax reforms introduced at the start of 2024 delivered an additional $98.8m in corporation tax for the Exchequer last year.

Those Pillar Two reforms mean firms with revenues in excess of €750m are subject to an effective minimum corporate tax rate of 15pc.

The accounts show that based on its pre-tax profits of $4.09bn, it would have had a 12.5pc corporation tax bill of $512.29m.

Regeneron Ireland DAC’s corporation tax bill increased by $98.8m due to “the impact of Pilla

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