What if you could take Ozempic or similar GLP-1 drugs without having to worry about their gut-churning side effects? An experimental treatment being developed by the company Neurogastrx just might offer that sought-after possibility.

On Friday, the company released the latest data from its Phase II trial of their oral drug NG101. Volunteers who took NG101 while also on semaglutide (the active ingredient of Ozempic and Wegovy) experienced many fewer bouts of nausea and vomiting, the trial showed. The findings suggest that NG101 can help keep people from losing their appetite for taking GLP-1s for obesity.

“GI side effects are the leading reason why people discontinue GLP-1 treatment within the first year,” Jim O’Mara, Neurogastrx CEO, told Gizmodo.

An effective but nauseating drug

Semag

See Full Page