China: A new study has revealed that bleeding during early pregnancy is associated with an increased risk of fetal malformations . Progesterone injections should be used cautiously in women without prior adverse pregnancy outcomes. “Further research is needed to explore the possible interaction between folate-associated status (FAS) and progesterone use on the risk of malformations,” the authors stated. The study, led by Jiang-Nan Wu and colleagues from the Obstetrics and Gynecology Hospital of Fudan University, Shanghai, was published in the European Journal of Medical Research. It evaluated the potential link between early pregnancy bleeding, progesterone supplementation, and folic acid use, aiming to clarify whether their combination influences the risk of congenital malformat

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