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With Palantir's stock plummeting more than 11% this week despite a better-than-expected earnings report , CEO Alex Karp took aim at investors betting against the software company.

Karp, who co-founded Palantir in 2003, went after short sellers in two separate interviews on CNBC this week. After "Big Short" investor Michael Burry revealed bets against Palantir and Nvidia , Karp on Tuesday accused short sellers of "market manipulation."

He repeated that message on Friday in an interview with CNBC's Sara Eisen, again knocking Burry's wager against the stock.

"To get out of his position, he had to screw the whole economy by besmirching the best financials ever ... that are helping the average p

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