Fantasy football rankings - updated defense (DST) Week 10 rankings for 2025. Read the top-accuracy fantasy football DEF rankings for NFL team defenses.

It's time for another exciting week of fantasy football, and finding a D/ST with upside can be the difference between winning and losing matchups ahead of the fantasy football playoffs. Use our updated Week 10 fantasy football defense (DST) rankings for 2025 to pinpoint the best team defense for your lineups. In the rankings below, you will see where the Chicago Bears, New York Jets, Buffalo Bills, Los Angeles Rams, Los Angeles Chargers, Cleveland Browns, Indianapolis Colts, Carolina Panthers, and New England Patriots defenses stand, among all other D/STs.

Our defense fantasy football rankings for Week 10are put together by Nick Mari

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