Autosomal Dominant Polycystic Kidney Disease Associated with Better Dialysis Survival: Study

A large two-cohort analysis published in BMC Nephrology has found that patients with autosomal dominant polycystic kidney disease experience better survival rates while on dialysis compared with patients who have other causes of kidney failure. The study examined data from 63,875 individuals initiating kidney replacement therapy and observed that those diagnosed with autosomal dominant polycystic kidney disease had a significantly lower mortality risk during dialysis treatment. Despite this advantage, the rates of cardiovascular, infection-related, and cancer-related deaths were similar between patients with and without the genetic disorder. These findings highlight that while the disease has a hereditary origin and distinct clinical course, its impact on long-term dialysis outcomes may