Key Takeaways

A new foldable heart patch repaired damaged heart tissue in early testing

The patch is made from stem cells and placed through a small incision with no surgery required

Mayo Clinic researchers say human trials could begin in as little as five years

MONDAY, Nov. 10, 2025 (HealthDay News) — A Mayo Clinic team has developed a new way to repair damaged hearts without open-heart surgery, and early results suggest it could one day help people with severe heart failure.

The team created a thin patch of lab-grown heart tissue using reprogrammed adult stem cells. The patch can be folded and placed on the heart through a small incision, instead of opening the chest.

In preclinical tests, the patch helped the heart pump better and reduced scarring, researchers said.

"For patients

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