UNC football has struggled in recent seasons against Wake Forest in Winston-Salem, losing three of the last four games in the Tobacco Road rivalry series.

Bill Belichick's Tar Heels (4-5, 2-3 ACC) face the Demon Deacons (6-3, 3-3) in Week 12 of the 2025 college football season on Saturday, Nov. 15 (4:30 p.m., CW Network ), at Allegacy Federal Credit Union Stadium. UNC needs to win two of its final three games to become bowl eligible.

The Heels have won four straight against Wake Forest, but each game was decided by one possession. According to oddsmakers, the Deacs are favored by six points vs. UNC this season in a game that is likely to be a low-scoring, defensive battle.

Here are predictions, picks and betting odds for the latest UNC vs. Wake Forest game.

UNC vs Wake Forest odds, mon

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