Maryland: Pregnancy loss affects up to 25 per cent of all pregnancies, with most miscarriages occurring in the first trimester and roughly half caused by genetic or chromosomal abnormalities . But when pregnancy loss occurs three or more times, identifying the underlying cause becomes significantly more challenging, and often remains unknown.

Now, two new studies presented at the Association for Molecular Pathology (AMP) 2025 Annual Meeting & Expo in Boston suggest that a cutting-edge technology known as optical genome mapping (OGM) may uncover genetic factors missed by traditional methods, offering new hope for families seeking answers.

Researchers at Dartmouth-Hitchcock Medical Center investigated whether OGM could detect harmful chromosomal changes in patients with a family hist

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