Workers with AFSCME Local 3299 began their two-day strike at UC Irvine Medical Center in Orange, CA on Monday, Nov. 17, 2025. The union includes patient care and technical workers. (Photo by Paul Bersebach, Orange County Register/SCNG)

Nearly 40,000 patient care and technical workers began their two-day strike Monday, Nov. 17, at 19 University of California medical centers and campuses.

Hundreds of protesters showed up at UC Irvine Medical Center in Orange and UC Riverside.

Three major unions had planned to strike Nov. 17-18 — making it the largest strike in UC’s history — but two of the labor groups reached tentative deals with the UC on Nov. 8 and 15.

Also see: 24,000 nurses with California Nurses Association reach deal with UC

The American Federation of State, County and Mun

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