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NFL picks, predictions against the spread Week 12: Chiefs bounce back against Colts, Eagles edge Cowboys

There was a little more normalcy with the Week 11 2025 NFL regular season results to feel more confident going into Sporting News' Week 12 game picks and predictions against the spread.

A busy slate of division games saw some fortunes changing plenty in the race for the playoffs. Everything will only get tighter and tougher down the stretch with only seven weeks left before the playoffs.

Here's diving into the latest fearless forecast of professional pigskin prognostications:

(Odds courtesy of Caesars Sportsbook )

Chiefs, L

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