Key Takeaways

New guidelines for Crohn’s disease recommend going to advanced drugs immediately

The guidelines recommend using these drugs first rather than using a step-up approach trying less-effective meds first

The update is meant to keep up with the current research

THURSDAY, Nov. 20, 2025 (HealthDay News) — New guidelines recommend doctors tackle Crohn’s disease head-on, calling for the use of cutting-edge drugs as early as possible to quell the autoimmune GI disorder as quickly as possible.

The updated American Gastroenterological Association guidelines reject a “ step-up ” approach in which people get more advanced drugs only after they’ve tried cheaper, less effective medications like steroids or immunomodulating drugs like thiopurines .

Instead, doctors should go strai

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