Days of Our Lives (Peacock) heads into Friday, November 21, 2025, with a charged slate that puts EJ DiMera’s secret science front and center and sets up a very public clash in the hospital halls. These Days of Our Lives spoilers dig into the photos and episode teases for November 21, with specifics on EJ, Dr. Rolf, Mark, Rachel, Brady, Sarah, Kayla, Susan, Aaron, and Sophia.

What happens on November 21 (Friday)

Kayla becomes suspicious of EJ. Kayla Brady (Mary Beth Evans) starts connecting dots after a run-in with Mark (Jonah Robinson), zeroing in on EJ DiMera’s (Dan Feuerriegel) latest scheme.

Dr. Rolf and Mark get to work in EJ’s lab. Dr. Wilhelm Rolf (Richard Wharton) and Mark roll up their sleeves on a “mysterious experiment” tied to EJ’s plans.

Rachel confronts Brady and Sara

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