At various points during the fantasy football season, injuries, bye weeks and breaking news can cause you to need reinforcements for your fantasy lineup. Every Friday throughout the 2025 NFL season, Matt Bowen will offer some late-week pickup options to help fill those holes, with an emphasis on deeper leagues.

Because of that, this column will focus mostly on players rostered in fewer than 50% of ESPN leagues, with occasional exceptions.

Justin Herbert and Bo Nix are on byes this week, so we will start with three available quarterbacks who have solid matchups. There is a group of wide receivers providing both volume and upside worthy of consideration, plus there are some running backs I see as potential flex options for deeper formats. As always, I'll give you a tight end to potent

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