Injuries are a major part of the NFL and NFL betting , and that's certainly the case again this week. We've seen a large number of starting quarterbacks impacted by injuries both this season as a whole and of late, and that's the case again in Week 12. As we do every week, here are the biggest NFL injuries that bettors need to know, and what NFL betting lines look like according to the latest SportsLine consensus odds . We will update this post with inactives lists for every team prior to kickoff.

Colts at Chiefs (1 p.m. ET)

KC RB Isiah Pacheco (knee, out)

KC WR Xavier Worthy (ankle, questionable)

This monster AFC clash is a big one for both sides, but especially a Chiefs team that's 5-5 and has lost six games in a season just three times since Andy Reid took over in 20

See Full Page