Nov 15, 2025; Provo, Utah, USA; BYU Cougars wide receiver Chase Roberts (2) makes a catch against Texas Christian University Horned Frogs cornerback Jevon McIver Jr. (20) but is called incomplete after a video review during the second half at LaVell Edwards Stadium. Mandatory Credit: Rob Gray-Imagn Images

The biggest game of the week in the Big 12 is set for Saturday night at Nippert Stadium.

The BYU Cougars (9-1, 6-1 Big 12) have just one loss in conference play, and they control their own destiny to the title game, where they'd likely rematch with Texas Tech. First, they'll have to get through the Cincinnati Bearcats (7-3, 5-2 Big 12), which looked like a contender itself before dropping its last two games to Utah and Arizona

If you are looking for some betting advice for the matchup, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.

Cincinnati vs. BYU game odds:

All college football odds via BetMGM

  • Spread: BYU -2.5 (-120), Cincinnati +2.5 (+100)
  • Money Line: BYU -145, Cincinnati +120
  • Over-Under: Over 55.5 (-110), Under 55.5 (-110)

Cincinnati vs. BYU prediction, pick:

Cincinnati's strength all season has been the offense led by quarterback Brendan Sorsby and running back Tawee Walker, but now, it faces a stingy BYU defense that allows just 321 yards per game.

The Cougars' offense has been a bit inconsistent with true freshman quarterback Bear Bachmeier, but star running back LJ Martin leads this unit and is closing in on a 1,000-yard season. That's a concern against a Cincy defense that struggles quite a bit, particularly against the run.

The Bearcats are trending in the wrong direction, and they could be in for a slugfest here.

Prediction: BYU 30, Cincinnati 23

Best Bet: BYU -2.5, Under 55.5

Cincinnati vs. BYU channel, start time, streaming:

Time: 8 p.m. ET

TV Channel: FOX

Live Stream: Fox Sports App

Watch Cincinnati vs. BYU on FuboTV (Free Trial)

Get more betting analysis and predictions at Sportsbook Wire.

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This article originally appeared on College Sports Wire: Cincinnati vs. BYU: Week 13 College Football Betting Odds, Prediction

Reporting by Tyler Nettuno, College Sports Wire / College Sports Wire

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