Oregon outside linebackers Matayo Uiagalelei, right, and Teitum Tuioti take the field as the Oregon Ducks host the Minnesota Golden Gophers on Nov. 14, 2025, at Autzen Stadium in Eugene, Oregon.

EUGENE, OR — Week 13 of the college football season centers on Autzen Stadium, where No. 5 Oregon takes on No. 16 Southern California in a Big Ten battle with major College Football Playoff implications.

The Ducks are ready to punch their ticket to the playoffs, all they need is a signature win to do it. Beating the Trojans would do that, but a loss will suddenly put Oregon in dangerous territory with a chance of being left out. The fate is basically the same for USC. Win, and the Trojans will significantly boost their chances of making the CFP for the first time. Lose and those playoff chances are dead for Lincoln Riley and company.

With so much on the line, which team will take the major step forward? USA TODAY Sports is bringing you live updates, scores and highlights from the game. Follow along.

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USC vs Oregon live score

TEAM Q1 Q2 Q3 Q4 FINAL
USC
Oregon

USC vs Oregon live updates

This section will be updated.

What time does USC vs Oregon start?

  • Date: Saturday, Nov. 22
  • Time: 3:30 p.m. ET, 12:30 p.m. PT
  • Where: Autzen Stadium (Eugene, Oregon)

Oregon vs. USC kicks off at 3:30 p.m. (12:30 p.m. local time) on Saturday, Nov. 22 from Autzen Stadium in Eugene, Oregon.

What TV channel is USC vs Oregon on today?

  • TV: CBS
  • Streaming: Fubo (free trial)

Oregon vs. USC will air nationally on CBS in Week 13. Brad Nessler (play-by-play) and Gary Danielson (analyst) will call the game from the booth while Jenny Dell will serve as the sideline reporter.

Streaming options include Fubo, which offers a free trial to potential subscribers.

USC vs Oregon predictions

  • Jordan Mendoza, USA TODAY: Oregon 34, USC 27
  • Chris Hansen, Eugene Register-Guard: Oregon 34, USC 24

USC vs Oregon predictions, picks, odds

Odds courtesy of BetMGM as of Saturday, Nov. 22:

  • Spread: Oregon (-10.5)
  • Over/under: 59.5
  • Moneyline: Oregon (-400); USC (+310)

Oregon WR Dakorien Moore injury update

Oregon's top receiver Dakorien Moore will not play against USC due to a knee injury. This will be the third straight game he will miss, a big blow as he's the leading receiver for the Ducks.

USC injury updates

Out

  • Jamaal Jarrett, DT
  • Eli Sanders, RB
  • Waymond Jordan, RB
  • Anthony Beavers Jr., LB
  • Prophet Brown, CB
  • DJ Jordan, WR
  • Bishop Fitzgerald, S
  • Caden Chittenden, K

Questionable

  • Kamari Ramsey, S
  • J'Onre Reed, C
  • Elijah Paige, OL

Oregon football schedule 2025

  • Saturday, Aug. 30: Oregon 59, Montana State 13
  • Saturday, Sept. 6: Oregon 69, Oklahoma State 3
  • Saturday, Sept. 13: Oregon 34, Northwestern 14
  • Saturday, Sept. 20: Oregon 41, Oregon State 7
  • Saturday, Sept. 27: Oregon 30, Penn State 24 (2OT)
  • Saturday, Oct. 4: BYE
  • Saturday, Oct. 11: Indiana 30, Oregon 20
  • Saturday, Oct. 18: Oregon 56, Rutgers 10
  • Saturday, Oct. 25: Oregon 21, Wisconsin 7
  • Saturday, Nov. 1: BYE
  • Saturday, Nov. 8: Oregon 18, Iowa 16
  • Friday, Nov. 14: Oregon 42, Minnesota 13
  • Saturday, Nov. 22: Oregon vs. USC | 3:30 p.m. ET | CBS
  • Saturday, Nov. 29: Oregon at Washington | TBD

USC football schedule 2025

  • Saturday, Aug 30: USC 73, Missouri State 13
  • Saturday, Sept. 6: USC 59, Georgia Southern 20
  • Saturday, Sept. 13: USC 33, Purdue 17
  • Saturday, Sept. 20: USC 45, Michigan State 31
  • Saturday, Sept. 27: Illinois 34, USC 32
  • Saturday, Oct. 4: BYE
  • Saturday, Oct. 11: USC 31, Michigan 13
  • Saturday, Oct. 18: Notre Dame 34, USC 24
  • Saturday, Oct. 25: BYE
  • Saturday, Nov. 1: USC 21, Nebraska 17
  • Friday, Nov. 7: USC 38, Northwestern 17
  • Saturday, Nov. 15: USC 26, Iowa 21
  • Saturday, Nov. 22: USC at Oregon | 3:30 p.m. ET | CBS
  • Saturday, Nov. 29: USC vs. UCLA | TBD

This article originally appeared on USA TODAY: USC vs Oregon live updates: Start time, TV channel for Week 13 game

Reporting by Jordan Mendoza, USA TODAY / USA TODAY

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