The Indianapolis Colts (8-5) and Seattle Seahawks (10-3) meet in a battle with playoff implications Sunday. Kickoff from Seattle, Washington, is set for 4:25 p.m. ET (CBS). Let's analyze BetMGM Sportsbook's NFL odds around the Colts vs. Seahawks odds and make our expert NFL picks and predictions for the best bets.

Indianapolis was routed 36-19 by the Jacksonville Jaguars in Week 14 while failing to cover as a 2.5-point road favorite as the Over (45) cashed. QB Daniel Jones suffered a season-ending injury in the loss, and while Indy has not named an official starter, all signs are pointing to former Colts star QB Philip Rivers , who retired in 2021 and is 44 years old, starting. The Colts have lost 3 straight and have failed to score over 20 in any of those losses.

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