Researchers at the Germans Trias i Pujol Research Institute (IGTP) have published a detailed analysis of 3D culture methods for colorectal cancer (CRC), offering a new resource for cancer researchers aiming to build more accurate lab-based tumor models. The study was published in Scientific Reports .

Three-dimensional tumor models are increasingly seen as essential tools for studying cancer biology and drug responses. Unlike traditional two-dimensional (2D) cultures, 3D multicellular tumor spheroids (MCTS) better replicate the architecture, cell-cell interactions, and oxygen and nutrient gradients of real tumors. However, producing consistent and physiologically relevant 3D models remains technically challenging, particularly across different CRC cell lines.

“This work is the result

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