The San Diego Padres (66-52) face the San Francisco Giants (59-59) in the opener of a 3-game set Monday. First pitch from Oracle Park in San Francisco is set for 9:45 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 4-2

The Friars took 2 of 3 from the Boston Red Sox over the weekend, culminated by a 6-2 winner Sunday. DH Luis Arraez went 2-for-4 with 2 RBIs. He had 2 hits in each game of the series over the weekend and is hitting .295 on the season. The Padres have won 4 of 5 and sit 2 games back in the NL West and are in the second Wild Card spot.

The Giants dropped 2 of 3 to the Washington Nationals over the weekend with an 8-0 stinker Sunday

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