The Miami Marlins (57-62) and the Cleveland Guardians (62-56) play the middle contest of a 3-game interleague series Wednesday at Progressive Field in Cleveland. First pitch is scheduled for 6:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Marlins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 1-0

The Guardians opened the interleague series Tuesday night with a 4-3 win over the Marlins as favorites (-130) with the Under (8.5) cashing.

Cleveland 3B Jose Ramirez went 3-for-4 with a double and a pair of solo homers. As a result, Ramirez became the franchise's multi-HR leader. He has 27 games with at least 2 homers in his 13-year career, breaking a tie with Hall of Famer Jim Thome and Alber

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