The Week 0 college football schedule kicks off on Saturday, Aug. 23. Big 12 title contenders meet in the first time slot of the season as Iowa State takes on Kansas State in Dublin, Ireland at noon ET. The latest Week 0 college football odds list Kansas State as the 3.5-point favorite, while the over/under is 49.5. Kansas State is the pre-season favorite to win the Big 12 at +500, while Iowa State is listed at +1300.

Other Week 0 college football lines of note include Kansas (-12.5) vs. Fresno State and Hawaii (-2.5) vs. Stanford. Who should you target in your Week 0 college football bets for those games and others? Before locking in any Week 0 college football picks, be sure to see the latest college football predictions from SportsLine's proven model . You can also get the latest bet3

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