TOPLINE:

Monthly administration of ivermectin for 3 consecutive months at the beginning of the short rainy season was associated with a lower incidence of malaria compared with albendazole in an area with high coverage and use of bed nets, with no safety concerns identified during the trial.

METHODOLOGY:

Malaria remains a significant global health issue, and rising mosquito resistance to insecticides undermines control measures. As a result, ivermectin, a broad-spectrum antiparasitic drug, has gained interest as a potential candidate to reduce malaria transmission.

Researchers conducted a cluster-randomized trial in Kwale, Kenya, to evaluate the efficacy and safety of mass ivermectin administration at the start of the short rainy season (October-December) for malaria transmission contr

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