Key takeaways:
Gildeuretinol helped patients maintain visual acuity for up to 7 years.
The oral therapy was well tolerated.
LONG BEACH, Calif. — Oral gildeuretinol helped patients with Stargardt disease maintain visual acuity for up to 7 years of treatment, according to a study.
Kenneth Fan, MD, MBA, discussed interim data from the TEASE-3 study at the American Society of Retina Specialists annual meeting.
“What we presented was essentially data looking at gildeuretinol , which is an investigational treatment for Stargardt disease, which reduces vitamin A dimerization and therefore reduces A2E and lipofuscin accumulation in photoreceptors and [retinal pigment epithelium],” Fan told Healio. “It does this by replacing a hydrogen with a deuterium molecule at carbon 20. It makes it h