The Philadelphia Phillies and the Seattle Mariners close out their three-game series on Wednesday. Philadelphia beat the Mariners 6-4 on Tuesday and has won three straight games. Meanwhile, Seattle has dropped four consecutive contests. Luis Castillo (8-6, 3.48 ERA) starts for the Mariners, and Jesus Luzardo (11-6, 4.21 ERA) counters for the Phillies.

First pitch from Citizens Bank Park is set for 1:05 p.m. ET. Philadelphia is a -144 favorite (risk $144 to win $100) in the latest Mariners vs. Phillies odds from DraftKings Sportsbook, while Seattle is a +118 underdog (risk $100 to win $118). The over/under for total runs scored is 8.5. Before making any Mariners vs. Phillies picks, be sure to see the MLB betting predictions from SportsLine's proven model.

Bet on Mariners vs. Phillies

See Full Page