Liverpool can expect a hostile reception when they travel to Newcastle on Monday amid their pursuit of wantaway Magpies striker Alexander Isak, while Manchester City and Tottenham face off in an early examination of their ambitions for the season.

Across Merseyside, a new era begins for Everton on Sunday when they welcome Brighton for the first competitive game at their new 53,000-capacity stadium.

AFP Sport looks at the major talking points ahead of the second weekend of the Premier League season:

Isak future hangs over Newcastle, Liverpool

Isak is set to sit out the meeting between his current employers and his preferred destination as a stand-off over the Swede's future rolls into the final week of the transfer window.

Newcastle insist the 25-year-old will not move unless they can

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