With more than 15 million Americans taking GLP-1 medications like Ozempic, Wegovy and Mounjaro, experts say patients could lose more than just fat if they aren't careful.

"The key to weight loss and especially weight loss maintenance is always going to be diet and exercise," said Dr. Peminda Cabandugama, of Cleveland Clinic's obesity medicine & endocrinology departments.

Studies have shown that 15-60% of weight loss for patients on GLP-1 medications is lean muscle mass. That means, if a patient loses 50 pounds, they could lose anywhere from 7.5 to 30 pounds of lean muscle.

That's why Cabandugama says strength and resistance training is crucial for people taking these medications.

"Things like free weights, things like the weight machines help. And a lot of my patients who might be a li

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