Key takeaways:

Ten-year predicted ASCVD risk of 4% or more may serve as an adequate threshold for statin initiation based on the PREVENT calculator.

Statin’s impact was marginal at lower thresholds but may yet benefit some.

Adopting 10-year atherosclerotic CVD risk thresholds based on the PREVENT equations may help guide statin initiation for the prevention of ASCVD events, according to a research letter published in JAMA Cardiology .

Prior research published in Circulation showed that Pooled Cohort Equations may overestimate CVD risk by approximately twofold.

Ten-year predicted ASCVD risk of 4% or more may serve as an adequate threshold for statin initiation based on the PREVENT calculator. Image: Adobe Stock

“Therefore, the Predicting Risk of Cardiovascular Disease Events (P

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