The No. 8 Alabama Crimson Tide start their 2025 campaign on the road against the Florida State Seminoles on Saturday. Kalen DeBoer's team enters Week 1 on the heels of a 9-4 season and looks to keep trending upward. They visit a Seminoles side that is coming off a very disappointing 2024 season where they finished at the bottom of the ACC with a 2-10 record.

Kickoff from Doak Campbell Stadium in Tallahassee is set for 3:30 p.m. ET. The Crimson Tide are 13.5-point favorites in the latest Alabama vs. Florida State odds from SportsLine consensus, while the over-under for total points scored is set at 50.5. Before making any Florida State vs. Alabama picks or same-game parlays, be sure to see the Week 1 college football predictions from SportsLine's proven model and check out the lates

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