Philadelphia Phillies starting pitcher Ranger Suarez (55) throws against the Milwaukee Brewers in the first inning at American Family Field in Milwaukee, Wisconsin.

The New York Mets (76-67) and the Philadelphia Phillies (83-60) play the second game of a 4-game series Tuesday. First pitch from Citizens Bank Park is set for 6:45 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Mets vs. Phillies odds and make our expert MLB picks and predictions for the best bets.

Season series: Mets lead 7-3

The Mets, who are playing their third straight road series, lost 1-0 to the Phillies Monday night. SP Nolan McLean picked up the loss despite allowing just 1 earned run in 5 1/3 innings. New York has dropped 3 in a row and is 3-4 in September. It sits 3 games ahead of the San Francisco Giants for the final NL Wild Card spot.

The Phillies received a dominant performance from SP Aaron Nola Monday as he pitched 6 shutout innings. Offensively, OF Nick Castellanos batted in the only run of the game with an RBI single in the second inning. Philadelphia has won 8 of its last 11 games and sits atop the NL East. It has the second-shortest odds to win the World Series (+650 at BetMGM Sportsbook), behind only the LA Dodgers (+425).

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Mets at Phillies projected starters

LHP Sean Manaea vs. LHP Ranger Suarez

Manaea (1-2, 5.60 ERA) makes his 10th start and 11th appearance. He has a 1.24 WHIP, 1.8 BB/9 and 11.8 K/9 through 45 innings.

  • Last start: No-decision, 3 2/3 IP, 5 ER, 8 H, 1 BB, 6 K in 10-8 victory at Detroit Tigers Sept. 1
  • 2025 road stats: 0-2, 6.53 ERA (20 2/3 IP, 15 ER), 1.40 WHIP, 25 H, 4 BB, 30 K in 5 games (4 starts)
  • Career vs. Phillies (regular season): 2-2, 4.99 ERA (30 2/3 IP, 17 ER), 1.17 WHIP, 9.4 K/9 in 7 games (5 starts)

Suarez (11-6, 2.89 ERA) makes his 23rd start. He has a 1.18 WHIP, 2.1 BB/9 and 8.4 K/9 through 137 innings.

  • Last start: Win, 6 IP, 0 ER, 6 H, 2 BB, 4 K in 2-0 victory at Milwaukee Brewers Thursday
  • 2025 home stats: 5-2, 3.68 ERA (71 IP, 29 ER), 1.23 WHIP, 8.7 K/9 in 12 starts
  • Career vs. Mets (regular season): 4-3, 3.52 ERA (53 2/3 IP, 21 ER), 1.40 WHIP, 6.7 K/9 in 9 starts and 7 relief appearances

Mets at Phillies odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:50 a.m. ET.

  • Moneyline (ML): Mets +110 (bet $100 to win $110) | Phillies -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Mets +1.5 (-200) | Phillies -1.5 (+165)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Mets at Phillies picks and predictions

Prediction

Phillies 4, Mets 2

Moneyline

BET PHILLIES (-135).

When it rains, it pours. For New York, that has been true throughout the season, as it loses games in bunches. The Mets sit in the bottom half of the league at 32-35 following a loss.

Similarly, the Phillies have made Citizens Bank a fortress. They have the best home record in the majors at 46-23. Suarez has pitched like an ace this season as well, so they should have an advantage on the mound.

Bet PHILLIES (-135).

Run line/Against the spread

PASS.

There's no playable run-line value, especially with the way both teams are batting. The Mets +1.5 (-200) as run-line underdogs are too expensive, while the Phillies -1.5 (+165) are too risky as favorites. Avoid a play here.

Over/Under

BET UNDER 8.5 (-110).

Both sides are trending toward the Under. The Phillies are 0-2-1 O/U in their last 3 contests and 2-6-2 O/U in their last 10. Their offense has stalled, scoring 4 or fewer runs in 5 of their last 6 games.

The Mets have gone 0-4-1 O/U in their last 5 games and have tallied just 5 runs over their last 3 outings. Considering those trends, take UNDER 8.5 (-110).

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This article originally appeared on Sportsbook Wire: New York Mets at Philadelphia Phillies odds, picks and predictions

Reporting by Nathan Beighle, Sportsbook Wire / Sportsbook Wire

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