San Francisco 49ers star tight end George Kittle will miss at least four games after being placed on the injured reserve list because of a hamstring injury, the team announced Tuesday.

Kittle injured the hamstring in the first half of the 49ers' season-opening win at Seattle on Sunday after he had caught four catches for 25 yards and a touchdown.

In his place, Jake Tonges and Luke Farrell will handle the tight end duties until at least the Week 6 game against Tampa Bay. Tonges, who grew up in the Bay Area , caught the game-winning touchdown pass on Sunday, his first career TD.

George Kittle #85 of the San Francisco 49ers looks on during the NFL 2025 game between San Francisco 49ers and Seattle Seahawks at Lumen Field on September 07, 2025 in Seattle, Washington. Steph Chambers

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