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The San Francisco 49ers will play the New Orleans Saints in Week 2 of the 2025 NFL season.

Kickoff is scheduled for 1 p.m. ET on Sunday, September 14, 2025, at the Caesars Superdome.

The game will be broadcast on FOX and can be streamed on NFL+.

Entering the game, the 49ers have a 1-0 record, while the Saints are 0-1.

Week 2 of the 2025 NFL season continues with the San Francisco 49ers traveling to Caesars Superdome to take on the New Orleans Saints on Sunday.

Here's what you need to know about how to watch the Saints vs. the 49ers , today's matchup , the NFL Week 2 schedule , and more.

What time does New Orleans Saints - San Francisco 49ers NFL game start tonight, Sunday, Sept. 14, 2025? When is 49ers-Saints football game today?

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