Israeli forces pressed on with a new ground offensive in Gaza City Wednesday as strikes overnight across the Palestinian territory killed at least 16 people, including women and children, hospital officials said.

Hundreds of thousands remained in the city, the territory’s largest and already in ruins from nearly two years of war and struggling with a famine.

The latest Israeli operation, which started Tuesday, further escalates a conflict that has roiled the Middle East and likely pushes any ceasefire farther out of reach. The Israeli military, which says it wants to “destroy Hamas’ military infrastructure” hasn’t given a timeline for the offensive, but there were indications it could take months.

Many have been attempting to relocate from the city, where 1 million people once lived, to

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