Sep 13, 2025; Miami Gardens, Florida, USA; Miami Hurricanes quarterback Carson Beck (11) reacts against the South Florida Bulls during the third quarter at Hard Rock Stadium. Mandatory Credit: Sam Navarro-Imagn Images

College GameDay heads to Miami Gardens for a rivalry matchup that has certainly lost a bit of luster in Week 4.

The game between Miami and Florida looked to be one of the top early season matchups of the year, but now, it seems like it could be the final nail in the coffin for Billy Napier's tenure in Gainesville. The Gators are 1-2 to start the season, and they hope to avoid a third-straight loss against a Hurricanes team that has already notched wins over Notre Dame and the South Florida team that beat UF in the Swamp.

Miami won this game in blowout fashion in Gainesville a year ago, and it's hoping to earn its second-straight win in the rivalry series, which was once annual but is now played only sporadically.

Stream Miami vs. Florida

If you are looking for some betting advice for the matchup, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.

Miami vs. Florida game odds

All college football odds via BetMGM

  • Spread: Miami -8.5 (-110), Florida +8.5 (-110)
  • Money Line: Miami -350, Florida +275
  • Over-Under: Over 50.5 (-115), Under 50.5 (-105)

Miami vs. Florida prediction, pick:

The Gators have the defense to potentially keep this one close, but that will likely hinge on the play of DJ Lagway, who has struggled tremendously and is coming off a five-interception game in last week's loss to LSU. The Hurricanes' defensive front could cause problems for Florida, and with an elite offensive line against a shorthanded Gators defensive line, they could ultimately score a lot more points than the Tigers managed last week.

Prediction: Miami 31, Florida 14

Best Bet: Miami -8.5, Under 50.5

Miami vs. Florida channel, start time, streaming:

Time: 7:30 p.m. ET

TV Channel: ABC

Live Stream: ESPN App

Get more betting analysis and predictions at Sportsbook Wire.

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This article originally appeared on College Sports Wire: Miami vs. Florida: Week 4 College Football Betting Odds, Prediction, Pick

Reporting by Tyler Nettuno, College Sports Wire / College Sports Wire

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