Katie Couric is starring in a playful new public service announcement with a serious message about colon cancer screening that also spoofs the viral Sydney Sweeney jeans ad.

The “Lead From Behind” PSA begins with a closeup of the former TODAY co-anchor wearing an open denim shirt that’s off her shoulder as the lies on her side propped on pillows.

Katie Couric joins the Colorectal Cancer Alliance in a PSA urging people to get screened for colon cancer. Courtesy Maximum Effort

“Speaking of genes, did you know that the majority of people who develop colon cancer are not genetically predisposed to the disease?” she asks.

As the camera pulls out for a wider shot, it shows Couric is actually lying on a hospital bed and wearing a hospital gown as healthcare workers prepare for a colonosco

See Full Page