The College Football Playoff picture is starting to take shape after over a month of action, and the Week 5 college football schedule includes several games with major implications. No. 3 Penn State vs. No. 6 Oregon is one of four ranked matchups we're in store for, with kickoff scheduled for 7:30 p.m. ET. The Ducks just hammered arch-rivals Oregon State 41-7 to move to 4-0, while the Nittany Lions are 3-0 but haven't played a power conference opponent yet.

However, the latest Week 5 college football odds list Penn State as the 3.5-point home favorite with the over/under for this Big Ten matchup at 52.5 points. Oregon +3.5 is one of our top Week 5 college football best bets and will be a crucial part of our Week 5 college football parlay. Before locking in your Week 5 college footba

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