Green Bay Packers at Dallas Cowboys odds, picks and predictions

Green Bay Packers defensive end Micah Parsons (1) against the Detroit Lions on Sunday, Sept. 7, 2025, at Lambeau Field in Green Bay, Wis.

The Green Bay Packers (2-1) visit the Dallas Cowboys (1-2) in a Week 4 showdown at "Jerry World" on Sunday Night Football. Kickoff from AT&T Stadium in Dallas is at 8:20 p.m. ET (NBC). Let's analyze BetMGM Sportsbook's NFL odds around the Packers vs. Cowboys odds and make our expert NFL picks and predictions for the best bets.

This game comes with a lot of hype as DE Micah Parsons faces his old team. After looking like the best team in the sport the first 2 weeks, the Packers cost the public a lot of money with the egg they laid last week in a 13-10 loss at the Cleveland Browns as 7.5-point favorites. QB Jordan Love was 18-for-25 for 183 yards, 1 TD and 1 INT. RB Josh Jacobs rushed 16 times for just 30 yards and caught 5 balls for 44 more. They just couldn't sustain drives and reached the red zone twice.

The Cowboys were dominated by the Chicago Bears 31-14 last week as 1-point favorites. QB Dak Prescott was 31-for-40 for 251 yards, 1 score and 2 picks. TE Jake Ferguson erupted for 13 catches for 82 yards. However, the loss was even more costly as WR CeeDee Lamb was lost due to a high-ankle sprain. WR George Pickens stepped up for 5 grabs for 68 yards and a score. Dallas is going to have to get the ball out quickly to thwart Green Bay's elite pass rush.

Play our free daily Pick’em Challenge and win! Play now!

Packers at Cowboys odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:46 a.m. ET.

Moneyline (ML): Packers -350 (bet $350 to win $100) | Cowboys +280 (bet $100 to win $280)
Against the spread (ATS): Packers -7 (-105) | Cowboys +7 (-115)
Over/Under (O/U): 47.5 (O: -105 | U: -115)

Packers at Cowboys key injuries

Packers

OG Aaron Banks (groin) doubtful
S Javon Bullard (concussion) questionable
WR Jayden Reed (shoulder) out, on IR
OT Zach Tom (oblique) out
WR Christian Watson (knee) out, on PUP

Cowboys

OG Tyler Booker (ankle) out
WR CeeDee Lamb (ankle) out

Packers at Cowboys picks and predictions

Prediction

Packers 28, Cowboys 10

Moneyline

The Pack are massive road favorites, and they should dominate. There is one thing to keep an eye on, though, as RT Zach Tom is out. Newly acquired Cowboys DT Kenny Clark could be a problem on that side.

Conversely, the Packers have one of the best EDGE duos in football with Parsons and Rashan Gary, who has 4.5 sacks already. They are going to be in Dallas' backfield all evening. That's going to force Prescott into some errant throws, and he doesn't have the weapons downfield without Lamb.

So SGP PACKERS ML + DAK PRESCOTT OVER 0.5 INTERCEPTIONS (-102).

PACKERS AT COWBOYS: Best props bets

Against the spread

First off, head over to FanDuel and take RASHAN GARY TO RECORD A SACK (-114). The Cowboys are going to be so worried about Parsons coming back to bite them, Gary could have 3. I like Parsons to get to Prescott, too, but he's overpriced at -144.

Also, I'm taking PACKERS -6.5 (-115) at FanDuel. If you'd rather take the -7 (-110) at BetMGM, go for it. It should clear, too.

Over/Under

Dallas is 1-2 O/U thus far, and Green Bay is 0-3 O/U, largely because of their defense. Dallas is going to need 2 touchdowns for this Over to have a chance, and I don't see it happening unless they throw some pick-6s.

Give me the UNDER 47.5 (-115).

FOOTBALL NEVER STOPS: Live games, analysis and more 7 days a week: Get ESPN+!

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @rdodsonsports on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:

This article originally appeared on Sportsbook Wire: Green Bay Packers at Dallas Cowboys odds, picks and predictions

Reporting by Ryan Dodson, Sportsbook Wire / Sportsbook Wire

USA TODAY Network via Reuters Connect